ε Subunit, an Endogenous Inhibitor of Bacterial F1-ATPase, Also Inhibits F0F1-ATPase
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چکیده
منابع مشابه
ε Subunit of Bacillus subtilis F1-ATPase Relieves MgADP Inhibition
MgADP inhibition, which is considered as a part of the regulatory system of ATP synthase, is a well-known process common to all F1-ATPases, a soluble component of ATP synthase. The entrapment of inhibitory MgADP at catalytic sites terminates catalysis. Regulation by the ε subunit is a common mechanism among F1-ATPases from bacteria and plants. The relationship between these two forms of regulat...
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Modification of the mitochondrial F1-ATPase ε subunit, enhancement of the ATPase activity of the IF1–F1 complex and IF1-binding dependence of the conformation of the ε subunit Giancarlo SOLAINI*, Alessandra BARACCA†, Edi GABELLIERI‡ and Giorgio LENAZ† *Scuola Superiore di Studi Universitari e di Perfezionamento S. Anna, Via G. Carducci, 40, 56127 Pisa, Italy, †Dipartimento di Biochimica, Univer...
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BACKGROUND Apoptolidin is a macrolide originally identified on the basis of its ability to selectively kill E1A and E1A/E1B19K transformed rat glial cells while not killing untransformed glial cells. The goal of this study was to identify the molecular target of this newly discovered natural product. RESULTS Our approach to uncovering the mechanism of action of apoptolidin utilized a combinat...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1999
ISSN: 0021-9258
DOI: 10.1074/jbc.274.48.33991